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国際骨粗鬆症学会誌の抄録
Article Osteoporosis International Publisher: Springer-Verlag London Ltd ISSN: 0937-941X (Paper) 1433-2965 (Online) DOI: 10.1007/s00198-005-1955-8 Issue: Online First Original Article Correlations between periodontitis and loss of mandibular bone in relation to systemic bone changes in postmenopausal Japanese women Yoshitomo Takaishi1 , Yuko Okamoto1, Takashi Ikeo2, Hirotoshi Morii3, Mitsuhiro Takeda4, Kazukuni Hide4, Tatsuo Arai4 and Kiichi Nonaka5 (1) Takaishi Dental Clinic, 3-32 Hojo-guchi, Himeji 670-0935, Japan (2) Department of Biochemistry, Osaka Dental University, Osaka, Japan (3) Osaka City University and Osaka Dental University, Osaka, Japan (4) Furuno Electric Co. Ltd., Nishinomiya, Japan (5) Elk Corporation, Tokyo, Japan Received: 25 May 2004 Accepted: 31 March 2005 Published online: 19 July 2005 Abstract A new method of measuring mandibular alveolar bone mineral density (BMD) was applied to 40 postmenopausal Japanese women aged 50?69 years exhibiting minimal to mild periodontal diseases. Lumbar spine BMD was measured by dual X-ray absorptiometry (DXA) and calcaneus speed of sound (SOS) by quantitative ultrasound (QUS). There were age-related decreases of alveolar BMD, calcaneus SOS and vertebral BMD. There were significant correlations between two of the respective bone mass values. Correlations between clinical dental findings and bone mass data including alveolar BMD, SOS and lumbar spine BMD were investigated. Significant correlations were demonstrated between alveolar BMD and calcaneus SOS or vertebral BMD. Alveolar BMD showed significant correlation with clinical dental findings including periodontal pocket depth and mobility as well as calcaneus SOS and lumbar spine BMD. Using multivariate analysis combinations of univariate predictors, including deoxypyridinoline (DPD), significantly predicted attachment levels. The SOS value was useful combined with other predictors for predicting attachment level. It was concluded that the new method of evaluating alveolar BMD is useful to predict systemic bone mass and strength as well as dental clinical findings. |